Manciano is one of the centres of the Maremma Tuscany. It boasts medieval origins and was founded by the Aldobrandeschi noble family.

Manciano is characterized by some of the most remarkable buildings:

• city wall, still practically intact today
• St. Leonard’s Church
Church of the Most Holy Annunziata
• Liberty style Fountain of Piazza Garibaldi, built in 1913 to celebrate the inauguration of the city’s aqueduct